Antibiotic choice

Before prescribing antibiotics physicians examine patients and determine their exact symptoms to identify the condition. Only bacterial infections should be treated with antibiotics. For some minor cases the use of antibiotics on the first stages is not recommended. Still if the condition deteriorates, the use of antibiotics is needed.

When the diagnosis is made a doctor prescribes an antibiotic correct for each individual case. Sometimes the application of antibiotic can be corrected or the other antibiotic is recommended.

A culture can be taken to understand if bacteria are causing the infection. In more serious cases when hospitalization is needed, special test on susceptibility of bacteria to antibiotics is taken.

Some types of antibiotic drugs are useful for the particular bacteria. If the cause of the infection is unclear, but suspected to be due to bacteria, the physician can suggest using stronger wide-spectrum antibiotic to suppress a large variety of bacteria.

Women can be more prone to antibiotic actions because they kill or suppress normal bacteria in the vagina. So, vaginal yeast infections can start developing after antibiotic treatment. Women often experience burning during urination, vaginal discharge and other symptoms of yeast infection. Doctors often recommend women during the treatment with antibiotics to use other medications or soon after the treatment with antibiotic drug to use antifungal medication.

Women should also remember that antibiotics can make birth control pills ineffective.

Pregnant women should not use antibiotics without first consulting a doctor. Some antibiotics can be very dangerous for the unborn baby.

If your doctor prescribes you Levofloxacin, you should know that there is a low possibility of bacteria to resist to this antibiotic. It is very effective and produces expanded gram-positive spectrum of activity.

Levofloxacin appears to be active against anaerobes, has a great effectiveness against lower respiratory tract pathogens.

Doctors often prescribe Levofloxacin for the treatment of nosocomial pneumonia. Besides, the medicine is effective against atypical respiratory pathogens such as Legionella pneumophila, Mycoplasma pneumoniae, Chlamydophila pneumoniae and resistant pneumococci.

Levofloxacin is often the drug of choice for patients with liver disease who are contraindicated to use other types of antibiotics.

The medicine does not interact with alcohol. Still its use with alcohol is not recommended.

If you start using this antibiotic you should be watchful for some of its possible side effects. It can increase the risk of tendon ruptures and postpone the healing of fractures especially in people of older age or taking corticosteroids.

Some people may experience arrhythmia and prolongation of the QT interval during use of Levofloxacin.

Patients with diabetes should control the level of blood sugar during the treatment with this antibiotic as it may increase the risk of dysglycemia.


Antibiotics are the medical tools used to treat and prevent various kinds of bacterial disorders from mild to severe ones. The use of antibiotics should be carefully considered in each individual case. The unwise use of antibiotics often leads to side effects, development of bacterial resistance to certain kinds of antibiotics and numerous health consequences.

The fact is not all antibiotics work for all kinds of microorganisms which provoke inflammation and disease in a human body. Antibiotics can be divided into groups of narrow spectrum and wide spectrum medicines. From the very name narrow spectrum are administered only for certain types of bacteria and are not effective for all the others.

Broad spectrum agents work against many types of bacteria and are used to treat various bacterial infections. The use of a particular type of antibiotic is based on the condition which a person suffers from, his personal history of allergic reactions to antibiotic agents, tolerability and response to the therapy. Besides, certain groups of patients such as pregnant women or children or people with chronic or acute kidney or liver disorders cannot use antibiotics or should be adjusted the alternative safe types of antibiotic agents.

As narrow spectrum antibiotics are only effective against a limited range of microorganisms, they are used for certain uncommon types of bacterial infections or infections of very serious character. They kill only bacteria which cause the disease. While broad spectrum antibiotics are often self-administered for a great number of infections from common sore throat to infections of the urinary tract. They kill every pathogen they meet on their way.

Certain groups of antibiotics target the infections of certain body organs and systems. For instance, bacterial infections of the gastrointestinal tract and upper respiratory tract can be treated by different antibiotics.

There is another division of all antibiotics to bactericidal and bacteriostatic.

Bactericidal antibiotics have a direct purpose to kill the bacteria in the human body. This type of antibiotics may injure the membranes of pathogens or destroy the DNA and RNA of bacteria.

Bacteriostatic antibiotics don’t allow bacteria growing in the body. The pathogens don’t die, but they can’t grow or replicate either. Then the immune system starts its work to get rid of these pathogenic bacteria. For instance, some antibiotics prevent the growth of bacteria by interfering in the process of protein formation and thus stop bacteria from developing. Lots of bacteriostatic antibiotics impair the ability of bacteria to replicate by depriving bacteria from important metabolites for making new DNA and RNA.

Levofloxacin origin and approved uses

Levofloxacin is a generic name of the antibiotic agent which comes in the formulation of many branded medicines such as Levaquin, Leva-Pak, Tavanic, Levoday, Cravit and others. The medicine belongs to the 3rd generation class of fluoroquinolones and is approved for use by the FDA.

Actually the medicine was discovered by one of the Japanese pharmacological companies. The purpose of this antibiotic was to ensure the excellent antibacterial potency of the medicine and decrease the toxicity for the body.

Today Levofloxacin can be found in all the parts of the world and used for various infectious diseases.

U.S. FDA approved this medicine for a variety of infectious diseases in their acute state or chronically ongoing.

In the list of approval uses there are:

Acute bacterial sinusitis

Acute bacterial exacerbation of chronic bronchitis

Nosocomial pneumonia

Community-acquired pneumonia

Complicated skin and skin structure infections

Uncomplicated skin and skin structure infections (mild to moderate) including abscesses, cellulitis, furuncles, impetigo, pyoderma, wound infections

Chronic bacterial prostatitis

Complicated urinary tract infections (mild to moderate)

Acute pyelonephritis (mild to moderate)

Uncomplicated urinary tract infections

Inhalational anthrax

Off-label uses (not approved by the FDA) include:

Helicobacter Pylori eradication

Pelvic inflammatory disease (PID)

Gynecological infections

Enterocolitis (Shigella)

Epididymitis (non-gonococcal)

Legionnaires disease



Community-acquired pneumonia in children

Typhoid fever


Levofloxacin can be considered one of the well-known medicines with proven effectiveness. The long years of its use have shown its advantages and weak sides.

Advantages of the medicine include its convenient and easy use. The dose is taken only once a day which excludes the missing or skipping doses. This is of course one of the benefits for patients who often forget about taking several doses of the medicine per day.

The other advantage of the medicine is its high effectiveness against broad spectrum of susceptible bacteria. It is bactericidal for many existing types of bacteria with fast onset of action.

Patients using this antibiotic rarely complain about side effects of this medicine. It is safe and well-tolerated by most patients. In comparison with other medicines from the same drug class of fluoroquinolones, Levofloxacin does not impose the risks of any cardiovascular effects, central nervous system disturbances and phototoxicity.

As the medicine has no P-450 metabolism, it does not significantly interact with other medicines.

Levofloxacin shows greater gram-positive spectrum of activity against Streptococcus pneumoniae than other fluoroquinolones.

Excellent bioavailability both orally and intravenously makes Levofloxacin a drug of choice for many bacterial disorders demanding extra strength and extra amounts of the active components.

Main disadvantages of the medicine involve the risks of certain side effects particularly risk of peripheral neuropathy, prolongation of QT, risks of tendon ruptures.

Important things to consider when buy Levofloxacin

tabletsThe right course of antibiotic therapy means that the antibiotic is chosen correctly and no pills are left in the pack after the treatment is completed. So with antibiotics it is very important to finish the treatment even if the positive result is observed in the first days of taking pills.

Levofloxacin antibiotic should also be used the full course without discontinuation. The reason to stop the treatment can be the risk for health produced by this particular medicine.

One package of Levofloxacin typically contains the right amount for one course of this antibiotic. Still in some cases your doctor may prescribe you taking this drug for a longer period of time.

Levofloxacin can work properly if it is used correctly. For most people the guidance on how to use antibiotics is a useful thing to have before and during the

To Levofloxacin refers the following:

•    Tablet form should not be broken into smaller pieces or crashed or chewed. It may prevent the medication from working properly.

•    Antibiotic Levofloxacin should be taken with water. Taking it together with fruit juices, dairy products or alcohol can affect the general well-being. Grapefruit juice and dietary supplements which contain minerals can make Levofloxacin less effective.

•    Levofloxacin can be used with food. Sometimes people cannot use this antibiotic alone as it irritates the stomach and produces very unpleasant feelings of pain and discomfort. So they can use Levofloxacin with foods to prevent the irritation.

•    Levofloxacin tablet must be used regularly, it is better to take it at the same time of day with or without meals.

•    Levofloxacin oral solution must be taken on an empty stomach 1 hour before or 2 hours after meals.

•    The antibiotic Levofloxacin should not be mixed with other antibiotics or drugs unless your doctor recommends you.

You can ask your doctor about buy Levofloxacin and its peculiarities. You can also find detailed information on the use of Levofloxacin in the package insert.

Warning information

risksLevofloxacin intake may involve higher risks for you if you have a muscle disorder. In case you are having a history of myasthenia gravis, talk to your doctor before buy Levofloxacin.

This antibiotic has a potential of risk to cause swelling and even rupture of a tendon (flexible but inelastic cord of strong fibrous collagen tissue attaching a muscle to a bone). The tendons of the heels are more prone to this risk.

The risk of rupture exists even after the treatment is stopped. So, people with tendon or tissue problems, people over 60 years of age or those who take steroids should inform their doctors before buy Levofloxacin.

How to prevent resistance to antibiotics?

bacteriaBeing careful while having the treatment with antibiotics can prevent resistance of bacteria and dangers to health. One should consider the following things before using any type of antibiotic.

The first thing to do is to visit a doctor and make sure that you really need the antibiotic therapy. Do not apply the antibiotic medicines if you have common cold, flu or any other condition not caused by bacteria.

Secondly you should follow all your doctor’s recommendations of use. The antibiotics should be used for the entire time period prescribed for you.

Very frequently the symptoms and signs of the bacterial condition disappear soon after you start the treatment with antibiotics. This in most cases does not mean that the infection is completely treated.resistance

It is important to continue the treatment even if your symptoms improved. The bacteria should be fully destroyed. Usually the treatment with antibiotics lasts for several days. Sometimes in cases of severe infections the treatment need longer time.

Do not self-treat! It may be dangerous for your health. Even if you have infection caused by bacteria, only a doctor can decide which type of antibiotic to choose. Today there are lots of antibiotics of wide spectrum of use. Still certain bacterial infections need to be treated with certain antibiotics.

pillsWhen you use antibiotic medicine, you help your body to recover from the disorder faster. However if it is possible to avoid using antibiotic, try not to use it. Persistent use of antibiotic medicines, overuse, too frequent use may make your immune system weaker and affect other body systems. The risk of bacteria resistance to antibiotics is increased when you use antibiotics too often.

To avoid any health consequences, consult your doctor before using any type of antibiotic. Never use too much of your medicine, take the recommended dose.