Antibiotics are the medical tools used to treat and prevent various kinds of bacterial disorders from mild to severe ones. The use of antibiotics should be carefully considered in each individual case. The unwise use of antibiotics often leads to side effects, development of bacterial resistance to certain kinds of antibiotics and numerous health consequences.
The fact is not all antibiotics work for all kinds of microorganisms which provoke inflammation and disease in a human body. Antibiotics can be divided into groups of narrow spectrum and wide spectrum medicines. From the very name narrow spectrum are administered only for certain types of bacteria and are not effective for all the others.
Broad spectrum agents work against many types of bacteria and are used to treat various bacterial infections. The use of a particular type of antibiotic is based on the condition which a person suffers from, his personal history of allergic reactions to antibiotic agents, tolerability and response to the therapy. Besides, certain groups of patients such as pregnant women or children or people with chronic or acute kidney or liver disorders cannot use antibiotics or should be adjusted the alternative safe types of antibiotic agents.
As narrow spectrum antibiotics are only effective against a limited range of microorganisms, they are used for certain uncommon types of bacterial infections or infections of very serious character. They kill only bacteria which cause the disease. While broad spectrum antibiotics are often self-administered for a great number of infections from common sore throat to infections of the urinary tract. They kill every pathogen they meet on their way.
Certain groups of antibiotics target the infections of certain body organs and systems. For instance, bacterial infections of the gastrointestinal tract and upper respiratory tract can be treated by different antibiotics.
There is another division of all antibiotics to bactericidal and bacteriostatic.
Bactericidal antibiotics have a direct purpose to kill the bacteria in the human body. This type of antibiotics may injure the membranes of pathogens or destroy the DNA and RNA of bacteria.
Bacteriostatic antibiotics don’t allow bacteria growing in the body. The pathogens don’t die, but they can’t grow or replicate either. Then the immune system starts its work to get rid of these pathogenic bacteria. For instance, some antibiotics prevent the growth of bacteria by interfering in the process of protein formation and thus stop bacteria from developing. Lots of bacteriostatic antibiotics impair the ability of bacteria to replicate by depriving bacteria from important metabolites for making new DNA and RNA.
Levofloxacin is a generic name of the antibiotic agent which comes in the formulation of many branded medicines such as Levaquin, Leva-Pak, Tavanic, Levoday, Cravit and others. The medicine belongs to the 3rd generation class of fluoroquinolones and is approved for use by the FDA.
Actually the medicine was discovered by one of the Japanese pharmacological companies. The purpose of this antibiotic was to ensure the excellent antibacterial potency of the medicine and decrease the toxicity for the body.
Today Levofloxacin can be found in all the parts of the world and used for various infectious diseases.
U.S. FDA approved this medicine for a variety of infectious diseases in their acute state or chronically ongoing.
In the list of approval uses there are:
Acute bacterial sinusitis
Acute bacterial exacerbation of chronic bronchitis
Complicated skin and skin structure infections
Uncomplicated skin and skin structure infections (mild to moderate) including abscesses, cellulitis, furuncles, impetigo, pyoderma, wound infections
Chronic bacterial prostatitis
Complicated urinary tract infections (mild to moderate)
Acute pyelonephritis (mild to moderate)
Uncomplicated urinary tract infections
Off-label uses (not approved by the FDA) include:
Helicobacter Pylori eradication
Pelvic inflammatory disease (PID)
Community-acquired pneumonia in children
Levofloxacin can be considered one of the well-known medicines with proven effectiveness. The long years of its use have shown its advantages and weak sides.
Advantages of the medicine include its convenient and easy use. The dose is taken only once a day which excludes the missing or skipping doses. This is of course one of the benefits for patients who often forget about taking several doses of the medicine per day.
The other advantage of the medicine is its high effectiveness against broad spectrum of susceptible bacteria. It is bactericidal for many existing types of bacteria with fast onset of action.
Patients using this antibiotic rarely complain about side effects of this medicine. It is safe and well-tolerated by most patients. In comparison with other medicines from the same drug class of fluoroquinolones, Levofloxacin does not impose the risks of any cardiovascular effects, central nervous system disturbances and phototoxicity.
As the medicine has no P-450 metabolism, it does not significantly interact with other medicines.
Levofloxacin shows greater gram-positive spectrum of activity against Streptococcus pneumoniae than other fluoroquinolones.
Excellent bioavailability both orally and intravenously makes Levofloxacin a drug of choice for many bacterial disorders demanding extra strength and extra amounts of the active components.
Main disadvantages of the medicine involve the risks of certain side effects particularly risk of peripheral neuropathy, prolongation of QT, risks of tendon ruptures.
The right course of antibiotic therapy means that the antibiotic is chosen correctly and no pills are left in the pack after the treatment is completed. So with antibiotics it is very important to finish the treatment even if the positive result is observed in the first days of taking pills.
Levofloxacin antibiotic should also be used the full course without discontinuation. The reason to stop the treatment can be the risk for health produced by this particular medicine.
One package of Levofloxacin typically contains the right amount for one course of this antibiotic. Still in some cases your doctor may prescribe you taking this drug for a longer period of time.
To Levofloxacin refers the following:
• Tablet form should not be broken into smaller pieces or crashed or chewed. It may prevent the medication from working properly.
• Antibiotic Levofloxacin should be taken with water. Taking it together with fruit juices, dairy products or alcohol can affect the general well-being. Grapefruit juice and dietary supplements which contain minerals can make Levofloxacin less effective.
• Levofloxacin can be used with food. Sometimes people cannot use this antibiotic alone as it irritates the stomach and produces very unpleasant feelings of pain and discomfort. So they can use Levofloxacin with foods to prevent the irritation.
• Levofloxacin tablet must be used regularly, it is better to take it at the same time of day with or without meals.
• Levofloxacin oral solution must be taken on an empty stomach 1 hour before or 2 hours after meals.
• The antibiotic Levofloxacin should not be mixed with other antibiotics or drugs unless your doctor recommends you.
You can ask your doctor about buy Levofloxacin and its peculiarities. You can also find detailed information on the use of Levofloxacin in the package insert.
This antibiotic has a potential of risk to cause swelling and even rupture of a tendon (flexible but inelastic cord of strong fibrous collagen tissue attaching a muscle to a bone). The tendons of the heels are more prone to this risk.
The risk of rupture exists even after the treatment is stopped. So, people with tendon or tissue problems, people over 60 years of age or those who take steroids should inform their doctors before buy Levofloxacin.
The first thing to do is to visit a doctor and make sure that you really need the antibiotic therapy. Do not apply the antibiotic medicines if you have common cold, flu or any other condition not caused by bacteria.
Secondly you should follow all your doctor’s recommendations of use. The antibiotics should be used for the entire time period prescribed for you.
Very frequently the symptoms and signs of the bacterial condition disappear soon after you start the treatment with antibiotics. This in most cases does not mean that the infection is completely treated.
It is important to continue the treatment even if your symptoms improved. The bacteria should be fully destroyed. Usually the treatment with antibiotics lasts for several days. Sometimes in cases of severe infections the treatment need longer time.
Do not self-treat! It may be dangerous for your health. Even if you have infection caused by bacteria, only a doctor can decide which type of antibiotic to choose. Today there are lots of antibiotics of wide spectrum of use. Still certain bacterial infections need to be treated with certain antibiotics.
When you use antibiotic medicine, you help your body to recover from the disorder faster. However if it is possible to avoid using antibiotic, try not to use it. Persistent use of antibiotic medicines, overuse, too frequent use may make your immune system weaker and affect other body systems. The risk of bacteria resistance to antibiotics is increased when you use antibiotics too often.
To avoid any health consequences, consult your doctor before using any type of antibiotic. Never use too much of your medicine, take the recommended dose.
The development of such antibiotics as Levofloxacin is a great discovery in the medicine. The medicines called antibiotics can fight very serious bacterial infections and save lives of people. Antibiotics prevent the widespread of microorganisms and improve the symptoms just soon after the treatment begins.
The diseases for which antibiotics should only be prescribed are caused by bacteria. Other conditions should not be treated with antibiotics. Besides, these medicines are prescribed only when the disease is strongly suspected or proven by lab tests to be caused by bacteria.
Doctors give prescriptions for antibiotics with accurate information about the dosage and the frequency of daily use. Patients should carefully follow the prescriptions to get the best results. Besides, it is necessary to continue the full prescribed time of treatment. If you stop soon after your symptoms improve, the infection may still exist in your body and can restart developing again.
The complete prescribed dose is required for taking to kill the bacteria or make them unable to develop. Half dosing or missing doses may lead to resistance of microbes to the antibiotics. Microbes mutate and adapt to antibiotic actions. This means that antibiotics may become unharmful for bacteria and they start growing even faster in your body.
Proper taking of antibiotics for the entire time period necessary for recovery can help prevent the development of drug-resistant bacteria.
Unfortunately antibiotics can kill not only harmful bacteria, but also good bacteria. By affecting good bacterial balance, antibiotics may spoil the natural protective functions of the stomach, vagina and other organs causing stomach upset, dysbacteriosis, and vaginal infections. So, the long use of antibiotics is not recommended and can be dangerous. Only in cases your doctor considers the prolonged use of antibiotics necessary, you should take these medicines for longer time.
The other problem with antibiotics is that they can change the effectiveness of other medicines and cause side effects or allergic reactions. Tell your doctor if you use other medicines or have any allergic reactions to the medicines especially to antibiotics.
Pregnant women and women who feed their babies with breast milk should be very careful with antibiotic choice. It is strictly recommended to visit a doctor for consultation. Lots of antibiotics are not prescribed for pregnant and breast-feeding women.